Director
Phone
+41 61 / 267 05 99
Phone2
+41 61 / 267 20 02
Fax
+41 61 / 267 20 02
Faculty of Psychology and Faculty of Medicine, Psychiatric University Clinics, University of Basel

Büro 117
Birmannsgasse 8
4055 Basel

Publications

  • 1: Schicktanz N, Schwegler K, Fastenrath M, Spalek K, Milnik A, Papassotiropoulos A, Nyffeler T, de Quervain DJ. Motor threshold predicts working memory performance in healthy humans. Ann Clin Transl Neurol. 2014 Jan;1(1):69-73. doi: 10.1002/acn3.22. Epub 2013 Dec 6. PubMed PMID: 25356384; PubMed Central PMCID: PMC4207507.
  • 2: Ackermann S, Hartmann F, Papassotiropoulos A, de Quervain DJ, Rasch B. No Associations between Interindividual Differences in Sleep Parameters and Episodic Memory Consolidation. Sleep. 2014 Oct 17. pii: sp-00429-14. [Epub ahead of print] PubMed PMID: 25325488.
  • 3: Fastenrath M, Coynel D, Spalek K, Milnik A, Gschwind L, Roozendaal B, Papassotiropoulos A, de Quervain DJ. Dynamic modulation of amygdala-hippocampal connectivity by emotional arousal. J Neurosci. 2014 Oct 15;34(42):13935-47. doi: 10.1523/JNEUROSCI.0786-14.2014. PubMed PMID: 25319690.
  • 4: Vogler C, Gschwind L, Coynel D, Freytag V, Milnik A, Egli T, Heck A, de Quervain DJ, Papassotiropoulos A. Substantial SNP-based heritability estimates for working memory performance. Transl Psychiatry. 2014 Sep 9;4:e438. doi: 10.1038/tp.2014.81. PubMed PMID: 25203169; PubMed Central PMCID: PMC4203010.
  • 5: Vukojevic V, Kolassa IT, Fastenrath M, Gschwind L, Spalek K, Milnik A, Heck A, Vogler C, Wilker S, Demougin P, Peter F, Atucha E, Stetak A, Roozendaal B, Elbert T, Papassotiropoulos A, de Quervain DJ. Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors. J Neurosci. 2014 Jul 30;34(31):10274-84. doi: 10.1523/JNEUROSCI.1526-14.2014. PubMed PMID: 25080589.
  • 6: Wilker S, Pfeiffer A, Kolassa S, Elbert T, Lingenfelder B, Ovuga E, Papassotiropoulos A, de Quervain D, Kolassa IT. The role of FKBP5 genotype in moderating long-term effectiveness of exposure-based psychotherapy for posttraumatic stress disorder. Transl Psychiatry. 2014 Jun 24;4:e403. doi: 10.1038/tp.2014.49. PubMed PMID: 24959896; PubMed Central PMCID: PMC4080328.
  • 7: Wilker S, Elbert T, Papassotiropoulos A, de Quervain DJ, Kolassa IT. Response to: Further Support for an Association between the Memory-Related Gene WWC1 and Posttraumatic Stress Disorder: Results from the Detroit Neighborhood Health Study. Biol Psychiatry. 2014 Dec 1;76(11):e27-8. doi: 10.1016/j.biopsych.2014.05.003. Epub 2014 May 15. PubMed PMID: 24947540.
  • 8: Harrisberger F, Spalek K, Smieskova R, Schmidt A, Coynel D, Milnik A, Fastenrath M, Freytag V, Gschwind L, Walter A, Vogel T, Bendfeldt K, de Quervain DJ, Papassotiropoulos A, Borgwardt S. The association of the BDNF Val66Met polymorphism and the hippocampal volumes in healthy humans: a joint meta-analysis of published and new data. Neurosci Biobehav Rev. 2014 May;42:267-78. doi: 10.1016/j.neubiorev.2014.03.011. Epub 2014 Mar 24. PubMed PMID: 24674929.
  • 9: Hadziselimovic N, Vukojevic V, Peter F, Milnik A, Fastenrath M, Fenyves BG, Hieber P, Demougin P, Vogler C, de Quervain DJ, Papassotiropoulos A, Stetak A. Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex. Cell. 2014 Mar 13;156(6):1153-66. doi: 10.1016/j.cell.2014.01.054. PubMed PMID: 24630719.
  • 10: Heck A, Fastenrath M, Ackermann S, Auschra B, Bickel H, Coynel D, Gschwind L, Jessen F, Kaduszkiewicz H, Maier W, Milnik A, Pentzek M, Riedel-Heller SG, Ripke S, Spalek K, Sullivan P, Vogler C, Wagner M, Weyerer S, Wolfsgruber S, de Quervain DJ, Papassotiropoulos A. Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity. Neuron. 2014 Mar 5;81(5):1203-13. doi: 10.1016/j.neuron.2014.01.010. Epub 2014 Feb 13. PubMed PMID: 24529980; PubMed Central PMCID: PMC4205276.
  • 11: Luksys G, Ackermann S, Coynel D, Fastenrath M, Gschwind L, Heck A, Rasch B, Spalek K, Vogler C, Papassotiropoulos A, de Quervain D. BAIAP2 is related to emotional modulation of human memory strength. PLoS One. 2014 Jan 2;9(1):e83707. doi: 10.1371/journal.pone.0083707. eCollection 2014. Erratum in: PLoS One. 2014;9(3):e92933. PubMed PMID: 24392092; PubMed Central PMCID: PMC3879265.
  • 12: Papassotiropoulos A, Gerhards C, Heck A, Ackermann S, Aerni A, Schicktanz N, Auschra B, Demougin P, Mumme E, Elbert T, Ertl V, Gschwind L, Hanser E, Huynh KD, Jessen F, Kolassa IT, Milnik A, Paganetti P, Spalek K, Vogler C, Muhs A, Pfeifer A, de Quervain DJ. Human genome-guided identification of memory-modulating drugs. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):E4369-74. doi: 10.1073/pnas.1314478110. Epub 2013 Oct 21. PubMed PMID: 24145423; PubMed Central PMCID: PMC3831994.
  • 13: Ackermann S, Hartmann F, Papassotiropoulos A, de Quervain DJ, Rasch B. Associations between basal cortisol levels and memory retrieval in healthy young individuals. J Cogn Neurosci. 2013 Nov;25(11):1896-907. doi: 10.1162/jocn_a_00440. Epub 2013 Jun 28. PubMed PMID: 23806175.
  • 14: Wilker S, Kolassa S, Vogler C, Lingenfelder B, Elbert T, Papassotiropoulos A, de Quervain DJ, Kolassa IT. The role of memory-related gene WWC1 (KIBRA) in lifetime posttraumatic stress disorder: evidence from two independent samples from African conflict regions. Biol Psychiatry. 2013 Nov 1;74(9):664-71. doi: 10.1016/j.biopsych.2013.02.022. Epub 2013 Apr 10. PubMed PMID: 23582269.
  • 15: Ackermann S, Heck A, Rasch B, Papassotiropoulos A, de Quervain DJ. The BclI polymorphism of the glucocorticoid receptor gene is associated with emotional memory performance in healthy individuals. Psychoneuroendocrinology. 2013 Jul;38(7):1203-7. doi: 10.1016/j.psyneuen.2012.10.009. Epub 2012 Nov 10. PubMed PMID: 23148886.
  • 16: Milnik A, Heck A, Vogler C, Heinze HJ, de Quervain DJ, Papassotiropoulos A. Association of KIBRA with episodic and working memory: a meta-analysis. Am J Med Genet B Neuropsychiatr Genet. 2012 Dec;159B(8):958-69. doi: 10.1002/ajmg.b.32101. Epub 2012 Oct 12. PubMed PMID: 23065961.
  • 17: Easton AC, Lourdusamy A, Loth E, Toro R, Giese KP, Kornhuber J, de Quervain DJ, Papassotiropoulos A, Fernandes C, Müller CP, Schumann G. CAMK2A polymorphisms predict working memory performance in humans. Mol Psychiatry. 2013 Aug;18(8):850-2. doi: 10.1038/mp.2012.114. Epub 2012 Jul 24. Erratum in: Mol Psychiatry. 2013 Aug;18(8):951. Torro, R [corrected to Toro, R]. PubMed PMID: 22824813.
  • 18: Mata R, Hau R, Papassotiropoulos A, Hertwig R. DAT1 polymorphism is associated with risk taking in the Balloon Analogue Risk Task (BART). PLoS One. 2012;7(6):e39135. doi: 10.1371/journal.pone.0039135. Epub 2012 Jun 18. PubMed PMID: 22723947; PubMed Central PMCID: PMC3377600.
  • 19: de Quervain DJ, Kolassa IT, Ackermann S, Aerni A, Boesiger P, Demougin P, Elbert T, Ertl V, Gschwind L, Hadziselimovic N, Hanser E, Heck A, Hieber P, Huynh KD, Klarhöfer M, Luechinger R, Rasch B, Scheffler K, Spalek K, Stippich C, Vogler C, Vukojevic V, Stetak A, Papassotiropoulos A. PKCα is genetically linked to memory capacity in healthy subjects and to risk for posttraumatic stress disorder in genocide survivors. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8746-51. doi: 10.1073/pnas.1200857109. Epub 2012 May 14. PubMed PMID: 22586106; PubMed Central PMCID: PMC3365172.
  • 20: Ackermann S, Spalek K, Rasch B, Gschwind L, Coynel D, Fastenrath M, Papassotiropoulos A, de Quervain DJ. Testosterone levels in healthy men are related to amygdala reactivity and memory performance. Psychoneuroendocrinology. 2012 Sep;37(9):1417-24. doi: 10.1016/j.psyneuen.2012.01.008. Epub 2012 Feb 15. PubMed PMID: 22341731.
  • 21: Vukojevic V, Gschwind L, Vogler C, Demougin P, de Quervain DJ, Papassotiropoulos A, Stetak A. A role for α-adducin (ADD-1) in nematode and human memory. EMBO J. 2012 Mar 21;31(6):1453-66. doi: 10.1038/emboj.2012.14. Epub 2012 Feb 3. PubMed PMID: 22307086; PubMed Central PMCID: PMC3321180.
  • 22: Heck A, Vogler C, Gschwind L, Ackermann S, Auschra B, Spalek K, Rasch B, de Quervain D, Papassotiropoulos A. Statistical epistasis and functional brain imaging support a role of voltage-gated potassium channels in human memory. PLoS One. 2011;6(12):e29337. doi: 10.1371/journal.pone.0029337. Epub 2011 Dec 21. PubMed PMID: 22216252; PubMed Central PMCID: PMC3244442.
  • 23: Papassotiropoulos A, Stefanova E, Vogler C, Gschwind L, Ackermann S, Spalek K, Rasch B, Heck A, Aerni A, Hanser E, Demougin P, Huynh KD, Luechinger R, Klarhöfer M, Novakovic I, Kostic V, Boesiger P, Scheffler K, de Quervain DJ. A genome-wide survey and functional brain imaging study identify CTNNBL1 as a memory-related gene. Mol Psychiatry. 2013 Feb;18(2):255-63. doi: 10.1038/mp.2011.148. Epub 2011 Nov 22. Erratum in: Mol Psychiatry. 2013 Feb;18(2):264. PubMed PMID: 22105620; PubMed Central PMCID: PMC3554877.
  • 24: Papassotiropoulos A, de Quervain DJ. Genetics of human episodic memory: dealing with complexity. Trends Cogn Sci. 2011 Sep;15(9):381-7. doi: 10.1016/j.tics.2011.07.005. Epub 2011 Aug 10. Review. PubMed PMID: 21835680.
  • 25: Vogler C, Gschwind L, Röthlisberger B, Huber A, Filges I, Miny P, Auschra B, Stetak A, Demougin P, Vukojevic V, Kolassa IT, Elbert T, de Quervain DJ, Papassotiropoulos A. Microarray-based maps of copy-number variant regions in European and sub-Saharan populations. PLoS One. 2010 Dec 16;5(12):e15246. doi: 10.1371/journal.pone.0015246. PubMed PMID: 21179565; PubMed Central PMCID: PMC3002949.
  • 26: Hauer D, Weis F, Papassotiropoulos A, Schmoeckel M, Beiras-Fernandez A, Lieke J, Kaufmann I, Kirchhoff F, Vogeser M, Roozendaal B, Briegel J, de Quervain D, Schelling G. Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapy. Crit Care Med. 2011 Apr;39(4):643-50. doi: 10.1097/CCM.0b013e318206bae6. PubMed PMID: 21169818.
  • 27: Dill MT, Duong FH, Vogt JE, Bibert S, Bochud PY, Terracciano L, Papassotiropoulos A, Roth V, Heim MH. Interferon-induced gene expression is a stronger predictor of treatment response than IL28B genotype in patients with hepatitis C. Gastroenterology. 2011 Mar;140(3):1021-31. doi: 10.1053/j.gastro.2010.11.039. Epub 2010 Nov 25. PubMed PMID: 21111740.
  • 28: Schneider A, Falkai P, Papassotiropoulos A. [Molecular principles of tau-induced toxicity: new experimental therapy strategies for treatment of Alzheimer's disease]. Nervenarzt. 2010 Nov;81(11):1289-90, 1292, 1294, passim. doi: 10.1007/s00115-010-3052-2. German. PubMed PMID: 20842339.
  • 29: Thal DR, Papassotiropoulos A, Saido TC, Griffin WS, Mrak RE, Kölsch H, Del Tredici K, Attems J, Ghebremedhin E. Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer's disease. Acta Neuropathol. 2010 Aug;120(2):169-83. doi: 10.1007/s00401-010-0707-9. Epub 2010 Jun 10. PubMed PMID: 20535486.
  • 30: Rasch B, Spalek K, Buholzer S, Luechinger R, Boesiger P, de Quervain DJ, Papassotiropoulos A. Aversive stimuli lead to differential amygdala activation and connectivity patterns depending on catechol-O-methyltransferase Val158Met genotype. Neuroimage. 2010 Oct 1;52(4):1712-9. doi: 10.1016/j.neuroimage.2010.05.054. Epub 2010 May 25. PubMed PMID: 20510373.
  • 31: Cathomas F, Vogler C, Euler-Sigmund JC, de Quervain DJ, Papassotiropoulos A. Fine-mapping of the brain-derived neurotrophic factor (BDNF) gene supports an association of the Val66Met polymorphism with episodic memory. Int J Neuropsychopharmacol. 2010 Sep;13(8):975-80. doi: 10.1017/S1461145710000519. Epub 2010 May 19. PubMed PMID: 20482942.
  • 32: Kolassa IT, Ertl V, Eckart C, Glöckner F, Kolassa S, Papassotiropoulos A, de Quervain DJ, Elbert T. Association study of trauma load and SLC6A4 promoter polymorphism in posttraumatic stress disorder: evidence from survivors of the Rwandan genocide. J Clin Psychiatry. 2010 May;71(5):543-7. doi: 10.4088/JCP.08m04787blu. Epub 2010 Apr 6. PubMed PMID: 20441718.
  • 33: Rasch B, Papassotiropoulos A, de Quervain DF. Imaging genetics of cognitive functions: Focus on episodic memory. Neuroimage. 2010 Nov 15;53(3):870-7. doi: 10.1016/j.neuroimage.2010.01.001. Epub 2010 Jan 11. Review. PubMed PMID: 20060913.
  • 34: Webster J, Reiman EM, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A, Rogers J, Heun R, Jessen F, Kölsch H, Heward CB, Ravid R, Hutton ML, Melquist S, Petersen RC, Caselli RJ, Papassotiropoulos A, Stephan DA, Hardy J, Myers A. Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis. Int J Mol Epidemiol Genet. 2010;1(1):19-30. Epub 2009 Jul 26. PubMed PMID: 21537449; PubMed Central PMCID: PMC3076748.
  • 35: Papassotiropoulos A, Henke K, Stefanova E, Aerni A, Müller A, Demougin P, Vogler C, Sigmund JC, Gschwind L, Huynh KD, Coluccia D, Mondadori CR, Hänggi J, Buchmann A, Kostic V, Novakovic I, van den Bussche H, Kaduszkiewicz H, Weyerer S, Bickel H, Riedel-Heller S, Pentzek M, Wiese B, Dichgans M, Wagner M, Jessen F, Maier W, de Quervain DJ. A genome-wide survey of human short-term memory. Mol Psychiatry. 2011 Feb;16(2):184-92. doi: 10.1038/mp.2009.133. Epub 2009 Dec 29. PubMed PMID: 20038948; PubMed Central PMCID: PMC3030750.
  • 36: Kolassa IT, Kolassa S, Ertl V, Papassotiropoulos A, De Quervain DJ. The risk of posttraumatic stress disorder after trauma depends on traumatic load and the catechol-o-methyltransferase Val(158)Met polymorphism. Biol Psychiatry. 2010 Feb 15;67(4):304-8. doi: 10.1016/j.biopsych.2009.10.009. Epub 2009 Nov 27. PubMed PMID: 19944409.
  • 37: Rasch B, Spalek K, Buholzer S, Luechinger R, Boesiger P, Papassotiropoulos A, de Quervain DJ. A genetic variation of the noradrenergic system is related to differential amygdala activation during encoding of emotional memories. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19191-6. doi: 10.1073/pnas.0907425106. Epub 2009 Oct 13. PubMed PMID: 19826083; PubMed Central PMCID: PMC2761241.
  • 38: Vogler C, Spalek K, Aerni A, Demougin P, Müller A, Huynh KD, Papassotiropoulos A, de Quervain DJ. CPEB3 is associated with human episodic memory. Front Behav Neurosci. 2009 May 4;3:4. doi: 10.3389/neuro.08.004.2009. eCollection 2009. PubMed PMID: 19503753; PubMed Central PMCID: PMC2691156.
  • 39: Hoerndli FJ, Walser M, Fröhli Hoier E, de Quervain D, Papassotiropoulos A, Hajnal A. A conserved function of C. elegans CASY-1 calsyntenin in associative learning. PLoS One. 2009;4(3):e4880. doi: 10.1371/journal.pone.0004880. Epub 2009 Mar 16. PubMed PMID: 19287492; PubMed Central PMCID: PMC2654071.
  • 40: Corneveaux JJ, Liang WS, Reiman EM, Webster JA, Myers AJ, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Craig DW, Coon KD, Dunckley T, Bandy D, Lee W, Chen K, Beach TG, Mastroeni D, Grover A, Ravid R, Sando SB, Aasly JO, Heun R, Jessen F, Kölsch H, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Papassotiropoulos A, Stephan DA, Huentelman MJ. Evidence for an association between KIBRA and late-onset Alzheimer's disease. Neurobiol Aging. 2010 Jun;31(6):901-9. doi: 10.1016/j.neurobiolaging.2008.07.014. Epub 2008 Sep 13. PubMed PMID: 18789830; PubMed Central PMCID: PMC2913703.
  • 41: Sigmund JC, Vogler C, Huynh KD, de Quervain DJ, Papassotiropoulos A. Fine-mapping at the HTR2A locus reveals multiple episodic memory-related variants. Biol Psychol. 2008 Oct;79(2):239-42. doi: 10.1016/j.biopsycho.2008.06.002. Epub 2008 Jun 14. PubMed PMID: 18602445.
  • 42: Tagarakis GI, Tsolaki-Tagaraki F, Tsolaki M, Diegeler A, Stylianakis GE, Kazis D, Tsilimingas NB, Papassotiropoulos A. Are genetic components related to cognitive decline after coronary artery surgery? Genetics and brain function after bypass heart surgery. J Card Surg. 2008 May-Jun;23(3):280-1. doi: 10.1111/j.1540-8191.2008.00577.x. PubMed PMID: 18435651.
  • 43: Buchmann A, Mondadori CR, Hänggi J, Aerni A, Vrticka P, Luechinger R, Boesiger P, Hock C, Nitsch RM, de Quervain DJ, Papassotiropoulos A, Henke K. Prion protein M129V polymorphism affects retrieval-related brain activity. Neuropsychologia. 2008;46(9):2389-402. doi: 10.1016/j.neuropsychologia.2008.03.002. Epub 2008 Mar 12. PubMed PMID: 18423780.
  • 44: Reiman EM, Chen K, Caselli RJ, Alexander GE, Bandy D, Adamson JL, Lee W, Cannon A, Stephan EA, Stephan DA, Papassotiropoulos A. Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions. Neuroimage. 2008 Apr 15;40(3):1214-21. doi: 10.1016/j.neuroimage.2007.12.066. Epub 2008 Jan 17. PubMed PMID: 18280754; PubMed Central PMCID: PMC2441925.
  • 45: Webster JA, Myers AJ, Pearson JV, Craig DW, Hu-Lince D, Coon KD, Zismann VL, Beach T, Leung D, Bryden L, Halperin RF, Marlowe L, Kaleem M, Huentelman MJ, Joshipura K, Walker D, Heward CB, Ravid R, Rogers J, Papassotiropoulos A, Hardy J, Reiman EM, Stephan DA. Sorl1 as an Alzheimer's disease predisposition gene? Neurodegener Dis. 2008;5(2):60-4. Epub 2007 Nov 1. PubMed PMID: 17975299.
  • 46: de Quervain DJ, Kolassa IT, Ertl V, Onyut PL, Neuner F, Elbert T, Papassotiropoulos A. A deletion variant of the alpha2b-adrenoceptor is related to emotional memory in Europeans and Africans. Nat Neurosci. 2007 Sep;10(9):1137-9. Epub 2007 Jul 29. PubMed PMID: 17660814.
  • 47: Tagarakis GI, Tsolaki-Tagaraki F, Tsolaki M, Diegeler A, Tsilimingas NB, Papassotiropoulos A. The role of apolipoprotein E in cognitive decline and delirium after bypass heart operations. Am J Alzheimers Dis Other Demen. 2007 Jun-Jul;22(3):223-8. PubMed PMID: 17606532.
  • 48: Tagarakis G, Tsolaki-Tagaraki F, Tsolaki M, Diegeler A, Kazis D, Rouska E, Papassotiropoulos A. The role of SOAT-1 polymorphisms in cognitive decline and delirium after bypass heart surgery. Clin Res Cardiol. 2007 Sep;96(9):600-3. Epub 2007 Jun 27. PubMed PMID: 17593314.
  • 49: Hoerndli FJ, Pelech S, Papassotiropoulos A, Götz J. Abeta treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. Eur J Neurosci. 2007 Jul;26(1):60-72. Epub 2007 Jun 22. PubMed PMID: 17587323.
  • 50: Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A, Heward CB, Ravid R, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Kukull W, Papassotiropoulos A, Stephan DA. GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron. 2007 Jun 7;54(5):713-20. PubMed PMID: 17553421; PubMed Central PMCID: PMC2587162.
  • 51: De Ferrari GV, Papassotiropoulos A, Biechele T, Wavrant De-Vrieze F, Avila ME, Major MB, Myers A, Sáez K, Henríquez JP, Zhao A, Wollmer MA, Nitsch RM, Hock C, Morris CM, Hardy J, Moon RT. Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9434-9. Epub 2007 May 21. PubMed PMID: 17517621; PubMed Central PMCID: PMC1890512.
  • 52: Coon KD, Myers AJ, Craig DW, Webster JA, Pearson JV, Lince DH, Zismann VL, Beach TG, Leung D, Bryden L, Halperin RF, Marlowe L, Kaleem M, Walker DG, Ravid R, Heward CB, Rogers J, Papassotiropoulos A, Reiman EM, Hardy J, Stephan DA. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J Clin Psychiatry. 2007 Apr;68(4):613-8. PubMed PMID: 17474819.
  • 53: Huentelman MJ, Papassotiropoulos A, Craig DW, Hoerndli FJ, Pearson JV, Huynh KD, Corneveaux J, Hänggi J, Mondadori CR, Buchmann A, Reiman EM, Henke K, de Quervain DJ, Stephan DA. Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance. Hum Mol Genet. 2007 Jun 15;16(12):1469-77. Epub 2007 Apr 30. PubMed PMID: 17470457.
  • 54: Wollmer MA, Sleegers K, Ingelsson M, Zekanowski C, Brouwers N, Maruszak A, Brunner F, Huynh KD, Kilander L, Brundin RM, Hedlund M, Giedraitis V, Glaser A, Engelborghs S, De Deyn PP, Kapaki E, Tsolaki M, Daniilidou M, Molyva D, Paraskevas GP, Thal DR, Barcikowska M, Kuznicki J, Lannfelt L, Van Broeckhoven C, Nitsch RM, Hock C, Papassotiropoulos A. Association study of cholesterol-related genes in Alzheimer's disease. Neurogenetics. 2007 Aug;8(3):179-88. Epub 2007 Mar 27. PubMed PMID: 17387528.
  • 55: Wollmer MA, Nitsch RM, Hock C, Papassotiropoulos A. Genetic association study on colony-stimulating factor 1 in Alzheimer's disease. Neurodegener Dis. 2006;3(6):334-7. PubMed PMID: 17192722.
  • 56: Pearson JV, Huentelman MJ, Halperin RF, Tembe WD, Melquist S, Homer N, Brun M, Szelinger S, Coon KD, Zismann VL, Webster JA, Beach T, Sando SB, Aasly JO, Heun R, Jessen F, Kolsch H, Tsolaki M, Daniilidou M, Reiman EM, Papassotiropoulos A, Hutton ML, Stephan DA, Craig DW. Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies. Am J Hum Genet. 2007 Jan;80(1):126-39. Epub 2006 Dec 6. PubMed PMID: 17160900; PubMed Central PMCID: PMC1785308.
  • 57: Mondadori CR, de Quervain DJ, Buchmann A, Mustovic H, Wollmer MA, Schmidt CF, Boesiger P, Hock C, Nitsch RM, Papassotiropoulos A, Henke K. Better memory and neural efficiency in young apolipoprotein E epsilon4 carriers. Cereb Cortex. 2007 Aug;17(8):1934-47. Epub 2006 Oct 31. PubMed PMID: 17077159.
  • 58: Papassotiropoulos A, Stephan DA, Huentelman MJ, Hoerndli FJ, Craig DW, Pearson JV, Huynh KD, Brunner F, Corneveaux J, Osborne D, Wollmer MA, Aerni A, Coluccia D, Hänggi J, Mondadori CR, Buchmann A, Reiman EM, Caselli RJ, Henke K, de Quervain DJ. Common Kibra alleles are associated with human memory performance. Science. 2006 Oct 20;314(5798):475-8. PubMed PMID: 17053149.
  • 59: Coon KD, Valla J, Szelinger S, Schneider LE, Niedzielko TL, Brown KM, Pearson JV, Halperin R, Dunckley T, Papassotiropoulos A, Caselli RJ, Reiman EM, Stephan DA. Quantitation of heteroplasmy of mtDNA sequence variants identified in a population of AD patients and controls by array-based resequencing. Mitochondrion. 2006 Aug;6(4):194-210. Epub 2006 Jul 21. PubMed PMID: 16920408.
  • 60: Coon KD, Siegel AM, Yee SJ, Dunckley TL, Mueller C, Nagra RM, Tourtellotte WW, Reiman EM, Papassotiropoulos A, Petersen FF, Stephan DA, Kirsch WM. Preliminary demonstration of an allelic association of the IREB2 gene with Alzheimer's disease. J Alzheimers Dis. 2006 Aug;9(3):225-33. PubMed PMID: 16914832; PubMed Central PMCID: PMC1555623.
  • 61: Koller MF, Papassotiropoulos A, Henke K, Behrends B, Noda S, Kratzer A, Hock C, Hofmann M. Evidence of a genetic basis of Morgagni-Stewart-Morel syndrome. A case report of identical twins. Neurodegener Dis. 2005;2(2):56-60. PubMed PMID: 16909048.
  • 62: Papassotiropoulos A, Lambert JC, Wavrant-De Vrièze F, Wollmer MA, von der Kammer H, Streffer JR, Maddalena A, Huynh KD, Wolleb S, Lutjohann D, Schneider B, Thal DR, Grimaldi LM, Tsolaki M, Kapaki E, Ravid R, Konietzko U, Hegi T, Pasch T, Jung H, Braak H, Amouyel P, Rogaev EI, Hardy J, Hock C, Nitsch RM. Cholesterol 25-hydroxylase on chromosome 10q is a susceptibility gene for sporadic Alzheimer's disease. Neurodegener Dis. 2005;2(5):233-41. PubMed PMID: 16909003.
  • 63: Maddalena AS, Papassotiropoulos A, Gonzalez-Agosti C, Signorell A, Hegi T, Pasch T, Nitsch RM, Hock C. Cerebrospinal fluid profile of amyloid beta peptides in patients with Alzheimer's disease determined by protein biochip technology. Neurodegener Dis. 2004;1(4-5):231-5. PubMed PMID: 16908995.
  • 64: Wollmer MA, Kapaki E, Hersberger M, Muntwyler J, Brunner F, Tsolaki M, Akatsu H, Kosaka K, Michikawa M, Molyva D, Paraskevas GP, Lütjohann D, von Eckardstein A, Hock C, Nitsch RM, Papassotiropoulos A. Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet. 2006 Jul 5;141B(5):534-6. PubMed PMID: 16752360.
  • 65: Papassotiropoulos A, Fountoulakis M, Dunckley T, Stephan DA, Reiman EM. Genetics, transcriptomics, and proteomics of Alzheimer's disease. J Clin Psychiatry. 2006 Apr;67(4):652-70. Review. PubMed PMID: 16669732; PubMed Central PMCID: PMC2259384.
  • 66: de Quervain DJ, Papassotiropoulos A. Identification of a genetic cluster influencing memory performance and hippocampal activity in humans. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4270-4. Epub 2006 Mar 7. PubMed PMID: 16537520; PubMed Central PMCID: PMC1390747.
  • 67: Papassotiropoulos A, Wollmer MA, Tsolaki M, Brunner F, Molyva D, Lütjohann D, Nitsch RM, Hock C. A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease. J Clin Psychiatry. 2005 Jul;66(7):940-7. PubMed PMID: 16013913.
  • 68: Papassotiropoulos A, Wollmer MA, Aguzzi A, Hock C, Nitsch RM, de Quervain DJ. The prion gene is associated with human long-term memory. Hum Mol Genet. 2005 Aug 1;14(15):2241-6. Epub 2005 Jun 29. PubMed PMID: 15987701.
  • 69: Papassotiropoulos A, Henke K, Aerni A, Coluccia D, Garcia E, Wollmer MA, Huynh KD, Monsch AU, Stähelin HB, Hock C, Nitsch RM, de Quervain DJ. Age-dependent effects of the 5-hydroxytryptamine-2a-receptor polymorphism (His452Tyr) on human memory. Neuroreport. 2005 May 31;16(8):839-42. PubMed PMID: 15891581.
  • 70: Kornblum C, Schröder R, Müller K, Vorgerd M, Eggers J, Bogdanow M, Papassotiropoulos A, Fabian K, Klockgether T, Zange J. Creatine has no beneficial effect on skeletal muscle energy metabolism in patients with single mitochondrial DNA deletions: a placebo-controlled, double-blind 31P-MRS crossover study. Eur J Neurol. 2005 Apr;12(4):300-9. PubMed PMID: 15804248.
  • 71: Papassotiropoulos A, Tsolaki M, Wollmer MA, Molyva D, Thal DR, Huynh KD, Tracy J, Staehelin HB, Monsch AU, Nitsch RM, Hock C. No association of a non-synonymous PLAU polymorphism with Alzheimer's disease and disease-related traits. Am J Med Genet B Neuropsychiatr Genet. 2005 Jan 5;132B(1):21-3. PubMed PMID: 15558716.
  • 72: Alberici A, Gobbo C, Panzacchi A, Nicosia F, Ghidoni R, Benussi L, Hock C, Papassotiropoulos A, Liberini P, Growdon JH, Frisoni GB, Villa A, Zanetti O, Cappa S, Fazio F, Binetti G. Frontotemporal dementia: impact of P301L tau mutation on a healthy carrier. J Neurol Neurosurg Psychiatry. 2004 Nov;75(11):1607-10. PubMed PMID: 15489396; PubMed Central PMCID: PMC1766923.
  • 73: Aerni A, Traber R, Hock C, Roozendaal B, Schelling G, Papassotiropoulos A, Nitsch RM, Schnyder U, de Quervain DJ. Low-dose cortisol for symptoms of posttraumatic stress disorder. Am J Psychiatry. 2004 Aug;161(8):1488-90. PubMed PMID: 15285979.
  • 74: Chen F, Wollmer MA, Hoerndli F, Münch G, Kuhla B, Rogaev EI, Tsolaki M, Papassotiropoulos A, Götz J. Role for glyoxalase I in Alzheimer's disease. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7687-92. Epub 2004 May 5. PubMed PMID: 15128939; PubMed Central PMCID: PMC419667.
  • 75: de Quervain DJ, Poirier R, Wollmer MA, Grimaldi LM, Tsolaki M, Streffer JR, Hock C, Nitsch RM, Mohajeri MH, Papassotiropoulos A. Glucocorticoid-related genetic susceptibility for Alzheimer's disease. Hum Mol Genet. 2004 Jan 1;13(1):47-52. Epub 2003 Oct 28. PubMed PMID: 14583441.
  • 76: de Quervain DJ, Henke K, Aerni A, Coluccia D, Wollmer MA, Hock C, Nitsch RM, Papassotiropoulos A. A functional genetic variation of the 5-HT2a receptor affects human memory. Nat Neurosci. 2003 Nov;6(11):1141-2. Epub 2003 Oct 19. PubMed PMID: 14566344.
  • 77: Maddalena A, Papassotiropoulos A, Müller-Tillmanns B, Jung HH, Hegi T, Nitsch RM, Hock C. Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to beta-amyloid peptide42. Arch Neurol. 2003 Sep;60(9):1202-6. PubMed PMID: 12975284.
  • 78: Wollmer MA, Streffer JR, Tsolaki M, Grimaldi LM, Lütjohann D, Thal D, von Bergmann K, Nitsch RM, Hock C, Papassotiropoulos A. Genetic association of acyl-coenzyme A: cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer's disease. Mol Psychiatry. 2003 Jun;8(6):635-8. PubMed PMID: 12851640.
  • 79: Hock C, Konietzko U, Streffer JR, Tracy J, Signorell A, Müller-Tillmanns B, Lemke U, Henke K, Moritz E, Garcia E, Wollmer MA, Umbricht D, de Quervain DJ, Hofmann M, Maddalena A, Papassotiropoulos A, Nitsch RM. Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease. Neuron. 2003 May 22;38(4):547-54. PubMed PMID: 12765607.
  • 80: Schmidt S, Papassotiropoulos A, Sotgiu S, Kölsch H, Arru G, Fois ML, Haase CG, Schmitz S, König N, Harzheim M, Heun R, Klockgether T. Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis. J Neurol. 2003 May;250(5):607-11. PubMed PMID: 12736743.
  • 81: Bagli M, Papassotiropoulos A, Hampel H, Becker K, Jessen F, Bürger K, Ptok U, Rao ML, Möller HJ, Maier W, Heun R. Polymorphisms of the gene encoding the inflammatory cytokine interleukin-6 determine the magnitude of the increase in soluble interleukin-6 receptor levels in Alzheimer's disease. Results of a pilot study. Eur Arch Psychiatry Clin Neurosci. 2003 Feb;253(1):44-8. PubMed PMID: 12664314.
  • 82: Wollmer MA, Streffer JR, Lütjohann D, Tsolaki M, Iakovidou V, Hegi T, Pasch T, Jung HH, Bergmann Kv, Nitsch RM, Hock C, Papassotiropoulos A. ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease. Neurobiol Aging. 2003 May-Jun;24(3):421-6. PubMed PMID: 12600718.
  • 83: Streffer JR, Papassotiropoulos A, Kurosinski P, Signorell A, Wollmer MA, Tsolaki M, Iakovidou V, Hörndli F, Bosset J, Götz J, Nitsch RM, Hock C. Saitohin gene is not associated with Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2003 Mar;74(3):362-3. PubMed PMID: 12588928; PubMed Central PMCID: PMC1738341.
  • 84: Schmidt S, Marrosu GM, Kölsch H, Haase CG, Ferenczik S, Sokolowski P, Köhler W, Schmidt M, Papassotiropoulos A, Heun R, Grosse-Wilde H, Klockgether T. Genetic variations and humoral immune responses to myelin oligodendroglia glycoprotein in adult phenotypes of X-linked adrenoleukodystrophy. J Neuroimmunol. 2003 Feb;135(1-2):148-53. PubMed PMID: 12576235.
  • 85: Papassotiropoulos A, Streffer JR, Tsolaki M, Schmid S, Thal D, Nicosia F, Iakovidou V, Maddalena A, Lütjohann D, Ghebremedhin E, Hegi T, Pasch T, Träxler M, Brühl A, Benussi L, Binetti G, Braak H, Nitsch RM, Hock C. Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. Arch Neurol. 2003 Jan;60(1):29-35. PubMed PMID: 12533085.
  • 86: Hock C, Konietzko U, Papassotiropoulos A, Wollmer A, Streffer J, von Rotz RC, Davey G, Moritz E, Nitsch RM. Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease. Nat Med. 2002 Nov;8(11):1270-5. Epub 2002 Oct 15. PubMed PMID: 12379846.
  • 87: Wollmer MA, Papassotiropoulos A, Streffer JR, Grimaldi LM, Kapaki E, Salani G, Paraskevas GP, Maddalena A, de Quervain D, Bieber C, Umbricht D, Lemke U, Bosshardt S, Degonda N, Henke K, Hegi T, Jung HH, Pasch T, Hock C, Nitsch RM. Genetic polymorphisms and cerebrospinal fluid levels of tissue inhibitor of metalloproteinases 1 in sporadic Alzheimer's disease. Psychiatr Genet. 2002 Sep;12(3):155-60. PubMed PMID: 12218659.
  • 88: Papassotiropoulos A, Lewis HD, Bagli M, Jessen F, Ptok U, Schulte A, Shearman MS, Heun R. Cerebrospinal fluid levels of beta-amyloid(42) in patients with Alzheimer's disease are related to the exon 2 polymorphism of the cathepsin D gene. Neuroreport. 2002 Jul 19;13(10):1291-4. PubMed PMID: 12151789.
  • 89: Papassotiropoulos A, Hock C. Biochemical markers of Alzheimer's disease: wish and reality. Neurobiol Aging. 2002 Jul-Aug;23(4):513-4. PubMed PMID: 12009497.
  • 90: Kockler M, Nitardy A, Papassotiropoulos A, Ptok U, Maier W, Heun R. Physical disorders and causes of death in relatives of Alzheimer's disease patients. Int J Geriatr Psychiatry. 2002 Apr;17(4):335-42. PubMed PMID: 11994887.
  • 91: Ptok U, Seeher C, Jessen F, Papassotiropoulos A, Heun R. Inter-rater reliability of family history information on psychiatric disorders in relatives. Eur Arch Psychiatry Clin Neurosci. 2001 Dec;251(6):279-83. PubMed PMID: 11881842.
  • 92: Majores M, Kolsch H, Bagli M, Papassotiropoulos A, Lohmann PL, Schmitz S, Rao ML, Maier W, Heun R. Cathepsin D: screening for new polymorphisms using single-strand conformation polymorphism analysis. Int J Mol Med. 2002 Feb;9(2):185-7. PubMed PMID: 11786931.
  • 93: Papassotiropoulos A, Lütjohann D, Bagli M, Locatelli S, Jessen F, Buschfort R, Ptok U, Björkhem I, von Bergmann K, Heun R. 24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. J Psychiatr Res. 2002 Jan-Feb;36(1):27-32. PubMed PMID: 11755458.
  • 94: Papassotiropoulos A, Hock C, Nitsch RM. Genetics of interleukin 6: implications for Alzheimer's disease. Neurobiol Aging. 2001 Nov-Dec;22(6):863-71. Review. PubMed PMID: 11754993.
  • 95: Ptok U, Papassotiropoulos A, Heun R. Mental health in spouses of patients with gerontopsychiatric disorders. Int J Geriatr Psychiatry. 2001 Oct;16(10):1014-6. PubMed PMID: 11607949.
  • 96: Jessen F, Flacke S, Granath DO, Manka C, Scheef L, Papassotiropoulos A, Schild HH, Heun R. Encoding and retrieval related cerebral activation in continuous verbal recognition. Brain Res Cogn Brain Res. 2001 Oct;12(2):199-206. PubMed PMID: 11587890.
  • 97: Jessen F, Kucharski C, Fries T, Papassotiropoulos A, Hoenig K, Maier W, Heun R. Sensory gating deficit expressed by a disturbed suppression of the P50 event-related potential in patients with Alzheimer's disease. Am J Psychiatry. 2001 Aug;158(8):1319-21. PubMed PMID: 11481170.
  • 98: Kölsch H, Ptok U, Bagli M, Papassotiropoulos A, Schmitz S, Barkow K, Kockler M, Rao ML, Maier W, Heun R. Gene polymorphisms of interleukin-1alpha influence the course of Alzheimer's disease. Ann Neurol. 2001 Jun;49(6):818-9. PubMed PMID: 11409442.
  • 99: Ptok U, Papassotiropoulos A, Maier W, Heun R. Seasonal distribution of births in patients with Alzheimer's disease and elderly depressive patients. Eur Psychiatry. 2001 Apr;16(3):157-61. PubMed PMID: 11353593.
  • 100: Ptok U, Papassotiropoulos A, Maier W, Heun R. Advanced parental age: a risk factor for Alzheimer's disease or depression in the elderly? Int Psychogeriatr. 2000 Dec;12(4):445-51. PubMed PMID: 11263711.
  • 101: Heun R, Kockler M, Papassotiropoulos A. Distinction of early- and late-onset depression in the elderly by their lifetime symptomatology. Int J Geriatr Psychiatry. 2000 Dec;15(12):1138-42. PubMed PMID: 11180471.
  • 102: Heun R, Papassotiropoulos A, Jessen F, Maier W, Breitner JC. A family study of Alzheimer disease and early- and late-onset depression in elderly patients. Arch Gen Psychiatry. 2001 Feb;58(2):190-6. PubMed PMID: 11177121.
  • 103: Schulze TG, Müller DJ, Krauss H, Scherk H, Ohlraun S, Syagailo YV, Windemuth C, Neidt H, Grässle M, Papassotiropoulos A, Heun R, Nöthen MM, Maier W, Lesch KP, Rietschel M. Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder. Am J Med Genet. 2000 Dec 4;96(6):801-3. PubMed PMID: 11121185.
  • 104: Bagli M, Papassotiropoulos A, Jessen F, Schmitz S, Rao ML, Maier W, Heun R. Identical distribution of the alpha 2-macroglobulin pentanucleotide deletion in subjects with Alzheimer disease and controls in a German population. Am J Med Genet. 2000 Dec 4;96(6):775-7. PubMed PMID: 11121179.
  • 105: Finckh U, von der Kammer H, Velden J, Michel T, Andresen B, Deng A, Zhang J, Müller-Thomsen T, Zuchowski K, Menzer G, Mann U, Papassotiropoulos A, Heun R, Zurdel J, Holst F, Benussi L, Stoppe G, Reiss J, Miserez AR, Staehelin HB, Rebeck GW, Hyman BT, Binetti G, Hock C, Growdon JH, Nitsch RM. Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease. Arch Neurol. 2000 Nov;57(11):1579-83. PubMed PMID: 11074789.
  • 106: Schmidt S, Papassotiropoulos A, Bagli M, Harzheim M, Heun R, Klockgether T. No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3'flanking region of the interleukin-6 gene in patients with multiple sclerosis. Neurosci Lett. 2000 Nov 24;294(3):139-42. PubMed PMID: 11072134.
  • 107: Papassotiropoulos A, Bagli M, Becker K, Jessen F, Maier W, Rao ML, Ludwig M, Heun R. No association between an intronic biallelic polymorphism of the FE65 gene and Alzheimer's disease. Int J Mol Med. 2000 Nov;6(5):587-9. PubMed PMID: 11029529.
  • 108: Jessen F, Block W, Träber F, Keller E, Flacke S, Papassotiropoulos A, Lamerichs R, Heun R, Schild HH. Proton MR spectroscopy detects a relative decrease of N-acetylaspartate in the medial temporal lobe of patients with AD. Neurology. 2000 Sep 12;55(5):684-8. PubMed PMID: 10980734.
  • 109: Majores M, Bagli M, Papassotiropoulos A, Schwab SG, Jessen F, Rao ML, Maier W, Heun R. Allelic association between the D10S1423 marker and Alzheimer's disease in a German population. Neurosci Lett. 2000 Aug 11;289(3):224-6. PubMed PMID: 10961670.
  • 110: Jessen F, Heun R, Erb M, Granath DO, Klose U, Papassotiropoulos A, Grodd W. The concreteness effect: evidence for dual coding and context availability. Brain Lang. 2000 Aug;74(1):103-12. PubMed PMID: 10924219.
  • 111: Papassotiropoulos A, Bagli M, Jessen F, Maier W, Förstl H, Kurz A, Heun R. Interaction of two genes possibly involved in the regulation of the amyloid precursor protein (APP) processing. Mol Psychiatry. 2000 May;5(3):240-1. PubMed PMID: 10889526.
  • 112: Schröder R, Vielhaber S, Wiedemann FR, Kornblum C, Papassotiropoulos A, Broich P, Zierz S, Elger CE, Reichmann H, Seibel P, Klockgether T, Kunz WS. New insights into the metabolic consequences of large-scale mtDNA deletions: a quantitative analysis of biochemical, morphological, and genetic findings in human skeletal muscle. J Neuropathol Exp Neurol. 2000 May;59(5):353-60. PubMed PMID: 10888364.
  • 113: Papassotiropoulos A, Lütjohann D, Bagli M, Locatelli S, Jessen F, Rao ML, Maier W, Björkhem I, von Bergmann K, Heun R. Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease. Neuroreport. 2000 Jun 26;11(9):1959-62. PubMed PMID: 10884051.
  • 114: Heun R, Papassotiropoulos A, Ptok U. Subthreshold depressive and anxiety disorders in the elderly. Eur Psychiatry. 2000 May;15(3):173-82. PubMed PMID: 10881214.
  • 115: Papassotiropoulos A, Bagli M, Jessen F, Frahnert C, Rao ML, Maier W, Heun R. Confirmation of the association between bleomycin hydrolase genotype and Alzheimer's disease. Mol Psychiatry. 2000 Mar;5(2):213-5. PubMed PMID: 10822352.
  • 116: Bagli M, Papassotiropoulos A, Knapp M, Jessen F, Luise Rao M, Maier W, Heun R. Association between an interleukin-6 promoter and 3' flanking region haplotype and reduced Alzheimer's disease risk in a German population. Neurosci Lett. 2000 Apr 7;283(2):109-12. PubMed PMID: 10739887.
  • 117: Papassotiropoulos A, Bagli M, Kurz A, Kornhuber J, Förstl H, Maier W, Pauls J, Lautenschlager N, Heun R. A genetic variation of cathepsin D is a major risk factor for Alzheimer's disease. Ann Neurol. 2000 Mar;47(3):399-403. PubMed PMID: 10716266.
  • 118: Lütjohann D, Papassotiropoulos A, Björkhem I, Locatelli S, Bagli M, Oehring RD, Schlegel U, Jessen F, Rao ML, von Bergmann K, Heun R. Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. J Lipid Res. 2000 Feb;41(2):195-8. PubMed PMID: 10681402.
  • 119: Bagli M, Papassotiropoulos A, Jessen F, Rao ML, Maier W, Heun R. Gene-gene interaction between interleukin-6 and alpha2-macroglobulin influences the risk for Alzheimer's disease. Ann Neurol. 2000 Jan;47(1):138-9. PubMed PMID: 10632118.
  • 120: Heun R, Klose U, Jessen F, Erb M, Papassotiropoulos A, Lotze M, Grodd W. Functional MRI of cerebral activation during encoding and retrieval of words. Hum Brain Mapp. 1999;8(4):157-69. PubMed PMID: 10619411.
  • 121: Schwab SG, Bagli M, Papassotiropoulos A, Jessen F, Maier W, Rao ML, Heun R. Alpha-1-antichymotrypsin gene polymorphism and risk for sporadic Alzheimer's disease in a German population. Dement Geriatr Cogn Disord. 1999 Nov-Dec;10(6):469-72. PubMed PMID: 10559561.
  • 122: Bagli M, Papassotiropoulos A, Schwab SG, Jessen F, Rao ML, Maier W, Heun R. No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer disease in a German population. J Neurol Sci. 1999 Aug 1;167(1):34-6. PubMed PMID: 10500259.
  • 123: Papassotiropoulos A, Heun R. Detection of subthreshold depression and subthreshold anxiety in the elderly. Int J Geriatr Psychiatry. 1999 Aug;14(8):643-50. PubMed PMID: 10489655.
  • 124: Papassotiropoulos A, Heun R. Screening for depression in the elderly: a study on misclassification by screening instruments and improvement of scale performance. Prog Neuropsychopharmacol Biol Psychiatry. 1999 Apr;23(3):431-46. PubMed PMID: 10378228.
  • 125: Papassotiropoulos A, Bagli M, Jessen F, Rao ML, Schwab SG, Heun R. Early-onset and late-onset depression are independent of the genetic polymorphism of apolipoprotein E. Dement Geriatr Cogn Disord. 1999 Jul-Aug;10(4):258-61. PubMed PMID: 10364642.
  • 126: Papassotiropoulos A, Bagli M, Jessen F, Bayer TA, Maier W, Rao ML, Heun R. A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease. Ann Neurol. 1999 May;45(5):666-8. PubMed PMID: 10319892.
  • 127: Papassotiropoulos A, Bagli M, Feder O, Jessen F, Maier W, Rao ML, Ludwig M, Schwab SG, Heun R. Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer's disease. Neurosci Lett. 1999 Mar 12;262(3):171-4. PubMed PMID: 10218883.
  • 128: Kühn KU, Meyer K, Nöthen MM, Gänsicke M, Papassotiropoulos A, Maier W. Allelic variants of dopamine receptor D4 (DRD4) and serotonin receptor 5HT2c (HTR2c) and temperament factors: replication tests. Am J Med Genet. 1999 Apr 16;88(2):168-72. PubMed PMID: 10206238.
  • 129: Papassotiropoulos A, Heun R, Maier W. The impact of dementia on the detection of depression in elderly subjects from the general population. Psychol Med. 1999 Jan;29(1):113-20. PubMed PMID: 10077299.
  • 130: Papassotiropoulos A, Hawellek B, Frahnert C, Rao GS, Rao ML. The risk of acute suicidality in psychiatric inpatients increases with low plasma cholesterol. Pharmacopsychiatry. 1999 Jan;32(1):1-4. PubMed PMID: 10071176.
  • 131: Heun R, Müller H, Papassotiropoulos A. Differential validity of informant-based diagnoses of dementia and depression in index subjects and in their first-degree relatives. Soc Psychiatry Psychiatr Epidemiol. 1998 Oct;33(10):510-3. PubMed PMID: 9780815.
  • 132: Rao ML, Hawellek B, Papassotiropoulos A, Deister A, Frahnert C. Upregulation of the platelet Serotonin2A receptor and low blood serotonin in suicidal psychiatric patients. Neuropsychobiology. 1998;38(2):84-9. PubMed PMID: 9732208.
  • 133: Heun R, Papassotiropoulos A, Jennssen F. The validity of psychometric instruments for detection of dementia in the elderly general population. Int J Geriatr Psychiatry. 1998 Jun;13(6):368-80. PubMed PMID: 9658272.
  • 134: Papassotiropoulos A, Heun R, Maier W. Age and cognitive impairment influence the performance of the General Health Questionnaire. Compr Psychiatry. 1997 Nov-Dec;38(6):335-40. PubMed PMID: 9406739.
  • 135: Rao ML, Pelzer E, Papassotiropoulos A, Tiemeier H, Jönck L, Möller HJ. Selective slow-wave sleep deprivation influences blood serotonin profiles and serum melatonin concentrations in healthy subjects. Biol Psychiatry. 1996 Oct 1;40(7):664-7. PubMed PMID: 8886302.
  • 136: Papassotiropoulos A, Ludwig M, Naib-Majani W, Rao GS. Induction of apoptosis and secondary necrosis in rat dorsal root ganglion cell cultures by oxidized low density lipoprotein. Neurosci Lett. 1996 May 3;209(1):33-6. PubMed PMID: 8734903.
  • 137: Rao ML, Bräunig P, Papassotiropoulos A. Autoaggressive behavior is closely related to serotonin availability in schizoaffective disorder. Pharmacopsychiatry. 1994 Sep;27(5):202-6. PubMed PMID: 7838891.